ABSTRACT
This work was conducted to evaluate the pharmacognostic and phytochemical study of varieties of Nagakesara. When it is further studied, it is observed that Nagakesara available in the markets of different areas is from different source plants. There are nearly 5 drugs sold in the market with the same name, the common floral parts available in the markets are commonly from Nagakesara (Mesua ferrea Linn.), Surapunnaga (Ochrocarpus longifolius Benth and Hook f.), Tamalpatra (Cinnamomum tamala Nees and Ebern.), Punnaga (Calophyllum inophyllum Linn.), Dillenia pentagyna Roxb. Hence a comparative study of these two samples 1) Nagakesara (Mesua ferrea), and 2) Tamalpatra (Cinnamomum tamala) has been carried out. The phytochemical study shows the presence of tannins, steroids and carbohydrates in almost all varieties of Nagakesara. Flower buds of Nagakesara plant of different species available in the market was taken up for the study. CONCLUSION: A detailed Pharamcognostic and Phytochemical review was done through which it was concluded that Mesua ferrea Linn. belonging to family Guttiferae may be the exact source of Nagakesara. The flower buds of Cinnamomum tamala Nees and Ebern. which is known as black variety in the markets according to our study,.
ABSTRACT
Background: Diabetic mellitus is a multifactorial disorder associated with its devastating consequences has assumed epidemic proportion in Bangladesh.Methods: The study evaluates the anti-hyperglycemic activity of the aqueous extracts of C. tamala (CTLEt) leaves in blood glucose of albino rats. Type II diabetes mellitus was induced by injecting alloxan at the concentration of 100mg/kg body weight in male albino rats. The diabetic rats were administered orally with aqueous CTLEt at the amount of 1.0ml, 1.5ml and 2.0ml with lab diet and glibenclamide (5mg/kg of body weight). Then blood glucose levels were estimated in all groups after 2 hours, 4 hours, 6 hours, 12 hours and 18 hours of the treatment with CTLEt and a known antidiabetic drug glibenclamide.Results: A comparison was made between the action of CTLEt and glibenclamide. Blood glucose levels of the CTLEt on 18th hours of the study were 8.6 to 5.1mmol/L (1ml CTLEt with lab diet), 10.4 to 4.9mmol/L (1.5ml CTLEt with lab diet), 14.7 to 4.3mmol/L (2.0ml CTLEt with lab diet) in comparison of diabetic control (9.5 to 8.5, 8.7 to 7.8, 7.7 to 7.1mmol/L) and glibenclamide (13.9 to 6.5, 16.3 to 6.1, 9.5 to 5.1mmol/L). Among the sample level, the 2.0ml CTLEt showed a higher efficiency of hypoglycemic effect on alloxan induced diabetic rats.Conclusions: Till date, there is no specific experimental work in Bangladesh about the evolution of antidiabetic activity of C. tamala plant in animal model. Further studies should be undertaken to find out the molecular mechanism of the leaf powder of C. tamala medicinal plant.
ABSTRACT
Seed characteristics and in vitro culture of C. tamala embryos were studied. Embryos desiccated below 50% (fresh weight) exhibited poor morphogenetic response in vitro and confirmed the recalcitrant nature of seeds. The immature embryos of various developmental ages (4-16 week after flowering, WAF) were cultured on different strengths of MS medium. Morphogenesis responses were recorded after 10 days of culture. The best culture responses were achieved from the immature embryos of 12 WAF on MS medium with sucrose (3%, w/v), polyvinyl pyrollidone (100 mg L-1) and benzyl adenine (12 µM). Under optimum condition ~60% explants responded; and ~7.3 shoots buds developed per explants after 35 days of culture initiation. The shoot buds could be converted into micro-shoots on MS medium with sucrose (3%) and kinetin (3 µM). About 5.3 micro-shoots/shoot buds sprouted per sub-culture. The micro-shoots were rooted by maintaining them on MS medium with α-naphthalene acetic acid (3 µM) where within 6-8 wk of culture ~8-10 roots developed. The rooted plantlets were acclimatized in vitro before they were transferred to community potting mix and maintained in the poly-shade ca 75% shading. The transplants registered ~70% survival after two months of transfer.
Subject(s)
Cinnamomum/drug effects , Cinnamomum/metabolism , Culture Media , Plant Shoots/drug effects , Plant Shoots/metabolism , Seeds/drug effects , Seeds/metabolism , Tissue Culture Techniques/methodsABSTRACT
Objective: To evaluate the variation of Cinnamomum tamala leaf essential oil in respect with months and tree size class. Methods: By fallowing standard laboratory methods using capillary GC-FID and GC-MS. Results: The oil samples were analyzed for two months and two different tree size classes. cinnamaldehyde, was the principal component, was higher in the both months i.e. October and January, highest in 30 cm girth class tree in January month (59.23%) and lowest in 60 cm girth class tree in a month of October (41.90%). Smaller size class tree contained greater amount of cinnamaldehyde as compared to higher size class. Conclusions: Consequences of the present study need to selection of proper, tree size and month for harsh economic potentials of such valuable resources.